It occurs in both sexes, with a preference for women aged 30-40 and men over 60. The incidence of MG is estimated at 5-30 cases / 1,000,000 persons per year and prevalence 10-20 cases. / 100,000.
It is an autoimmune disease because the immune system produces antibodies against acetylcholine receptors. Acetylcholine is an important substance, which acts as a neurotransmitter in neuromuscular synapses, to the point that it connects the nerve to the muscle. The reduced number of receptors results in weakness..
Gravis myasthenia is sometimes associated with thymic tumor or hyperplasia, thyrotoxicity, rheumatoid arthritis, or systemic lupus erythematosus. Also some medicines can trigger a myasthenic crisis.
Learn about Gravis Myasthenia.
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